Objective:1 To provide another valuable approach in detecting right ventrichlar function using echocardiography by the study on RV dyssynchrony in patients with PH.2 To determine whether right ventricular dyssynchrony is present in patients with pulmonary hypertension (PH) using longitudinal strain imaging, and analyze the correlation of RV dyssynchrony strain parameters with right ventricular(RV) function parameters and structure parameters in order to provide a valuable parameter for clinical evaluation of right ventricular function.Methods:1 The study population consisted of 60 patients with PH (patient group, male 21 and famale 39), in all, 9 patients with primary pulmonary hypertension, 12 patients with congenital heart disease, 11 patients with chronic thrombembolic, 13 patients with chronic obstructive pulmonary disease, 15 patients with connectibe tissue disorder. The PH patients divided into 3 groups based on the values of pulmonary artery Systolic pressure(PASP), each group contained 20 patients. Group A is mild PH Patients (30mmHg≤PASP0.05).Control group had slower heart rate than group A, but this not reach statistical significance(p>0.05), but, the difference had statistical significance(P0.05), but group B and group C were significance larger than control group(p0.05), the parameters mentioned above in group B and group C were significance larger than control group(p0.05), but , there were significant difference in control group compaired with group B and group C.Compared with control group, PH groups had significantly larger Max-△PST and Max-△TQ-S(p0.05); Max-△TQ-S had no statistical significance(p>0.05) between group B and group C.3 Correlation analysis of RV strain parameters with RV structure and function parameters3.1 Max-△TQ-S had strong correlation with PASP(r=0.81; P < 0.001). Max-△TQ-S had better correlation with RVESA, RVFAC , RVAD/LVTD, Tei-index and Ea ( r=0.62, p<0.001; r=-0.71, p<0.001; r=0.71, p<0.001; r=0.68, p<0.001;r=-0.66,p<0.001, respectively), it had good correlation with RVEDA , RATD and Ea /Aa (r=0.44,p<0.01;r=0.48, p<0.01;r=-0.48, p<0.01, respectively).3.2 Max-△PST had good correlation with PASP(r=0.48, p<0.01), it had some correlation with Tei-index, Ea and Ea /Aa (r=0.41, p<0.05;r=-0.45, p<0.05;r=-0.42,p<0.05, respectively).Conclusion:1 Strain imaging as a new ultrasound technology, which temporal and spatial resolution are both high, can accurately reflected the regional myocardial systolic activities, recognite the nuances in different segments of myocardial deformation in space and time distribution. Strain imaging is a valuable method detecting RV function by echocardiogrophy.2 Patients with PH exhibit right ventricular dyssynchrony,and has signifisently difference in mild PH group. RV dyssynchrony parameter has the following advantages,such as sensitive, curve smoothing, easy to measure, not be affected by cardiac geometry, having good correlation with right ventricular function and structure parameters,et al. We think right ventricular dyssynchrony parameter could evaluate right ventricular function in PH patients earlier.

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