Objectives: The assocoation between Hs-CRP in the blood of MS patients which can reflect the difference of syndrome and type,and the objective indexes integrated theoretical basis of combined medicine treatment.Methods: According to IDF diagnosis criteria and TCM dialectic criteria, we selected 100 cases(52 male and 48 female) and divided them into six Chinese medicine syndrome groups which include phlegm-dampness accumulation syndrome(23) 、 phlegm accumulation and blood stasis syndrome(21)、 Yin deficiency and heat excess syndyome(17)、 Qin and Yin deficiency syndrome(19)、 hyperactivity of fire due to Yin deficiency(13)、 deficiency of Yin and Yang(7).20 healthy people(ll male and 9 female) were taken as control group.(1) We take their blood pressure and waistline on an empty stomach.(2) We detected fasting plasma glucose(FPG), fasting insulin(FIns), triglyceride(TG) and high density lipoprotein-cholesterol(HDL-C), hs-CRP through taking suction from Venous blood.(3) The reverse of the product of FPG and Fins is used as the insulin sensitivity index(ISI): (ISI)=-ln(FPGXXFIns)Results: The hs-CRP in MS group is higher than it in the normal group(p < 0.05). In MS group, the rate of hs-CRP is working up by hyperactivity of fire due to Yin deficiency < phlegm-dampness accumulation syndrome < phlegm accumulation and blood stasis syndrome < Yin deficiency and heat excess syndyome < Qin and Yin deficiency syndrome < deficiency of Yin and Yang(p < 0.05).So hs-CRP can be taken as the objective signs of Chinese medicine syndromes.Conclusions: 1. The hs-CRP in MS group is higher than it in thenormal group. And there are difference between them.2. The rate of hs-CRP is working up by hyperactivity of fire due toYin deficiency < phlegm-dampness accumulation syndrome < phlegmaccumulation and blood stasis syndrome < Yin deficiency and heatexcess syndyome < Qin and Yin deficiency syndrome < deficiencyof Yin and Yang. There are difference in them.3.Hs-CRP can be taken as one of the objective signs of Chinesemedicine syngromes.