Objection:Lower limb deep vein thrombosis (DVT) is a common surgical disorder due to multiple pathogenic factors. In the process of DVT, a lot of inflammatory factors .include Interleukin-6 (IL-6) and Interleukon-10 (IL-10) will be released. In this study, the levels of IL-6 and IL-10 of plasma were assayed in order to determine there variations in the patients with DVT.Methods:The samples were collected from 100 inpatients with DVT in Department of General Surgery, Bohai Oil Hospital, from July 2003 to April 2006, and 100 normal control adults. The levels of plasma inflammatory factors Interleukin-6 (IL-6) and Interleukon-10 (IL-10) were determined on 0, 12, 24, 48, and 144 hours following treatment individually in DVT group by using ELISA reagent kit, and compared separately with normal control group. The variations of inter subgroups of each assay time points were compared too.Results:In DVT group, IL-6 reaches its peak at 0 hour. IL-6 levels at 0, 12 and 24 hours appear significant difference comparing with normal control, but no difference is found between any time points of IL-6 assay. The IL-10 level reaches its peak at 24 hour after admission. There is significance at 12 and 24 hours comparing with normalcontrol, and these levels at 12, 24 hours are significantly higher than them at 0 and 144 hours.Conclusions:In the progression of DVT, the levels of IL-6 and IL-10 are significantly higher than normal control at each investigating points.